COMPUTATIONAL LIFE EXPERIENCE

WHAT WE DO?

We design and optimize medical devices using the Digital Avatar, a digital version of the human body.

With it, it is possible to:

The Digital Avatar Platform reduces time and costs associated with the research and development of medical devices in pre-clinical and clinical phases.

It is a highly innovative testing platform that integrates several components of the human body in a tightly integrated manner and represents
the solution for MedTech companies that need to understand the effect of medical devices on the whole body. It solves the uncertainties connected
to animal testing and multiple parameter measurements at several locations.

MATHEMATICS AND MEDICINE COME TOGETHER

DIGITAL REVOLUTION

Towards In-Silico Clinical Trials

Quantify the effect of medical devices in a cohort of a virtual population has always been challenging in the modeling community for the lack of coupled interactive dynamics. 

A whole-body physiological model, coupled with a multiscale model of the whole body (3D-0D-1D) will enable the company to quantify the human response in a virtual population of human bodies

MATHEMATICS AND MEDICINE COME TOGETHER

SOFTWARE VALIDATION

Computational Life’s software replicates all body fluid mechanisms into a single, integrated platform based on the state-of-the-art of mathematical modeling. Our software is currently able to simultaneously simulate the dynamics of the:

• Arterial and venous system;
• Heart;
• Microcirculation;
• Pulmonary circulation;
• Cerebrospinal fluid;

The mathematical modeling relies on basic validated physical laws of fluid dynamics. The hemodynamics of the Digital Avatar have been validated using peer-reviewed articles in the healthy human body, and the computational waveforms closely resemble in-vivo measurements in healthy subjects.